SCE analysis in children exposed to lead emission from a smelting plant.

The frequency and location of SCE were evaluated in lymphocytes from peripheral blood cultures of 19 children living in a widely contaminated area and showing an increased absorption of lead. In the comparison between the exposed children and a control group living in an uncontaminated area, no significant differences were found in the mean values of SCE frequencies. The distributions of the SCE between chromosomes were proportional to chromosome length in both groups.

[Non-rachitic hypophosphatemic osteopathy].

We have identified a patient with a condition called Hypophosphatemic Bone Disease (HBD). This disorder of phosphate metabolism is unrecorded by Dent in his final classification of metabolic bone diseases and has been described by Scriver C.R.

["Follow-up milk": general principles and evaluation of the nutritional status of 100 subjects fed a liquid transitional formula].

Many authors have pointed that precocious weaning expose infants to serious risks as hypernutrition, obesity, adverse reactions to foods, hypernatremia, dental caries, emotional problems as anorexia or bulimia, so that actually weaning is delayed after 6th month of age. Going on with the "adapted" formula is a relative nonsense because "adapted" milks have low protein and calcium contents so that they are not adequate to cover estimated and advisable intakes of 4-6 month baby unless feeding unusual higher volumes. On the other side "fresh milk" can not be considered a nutritional "chance", owing its low values of EFA, iron, vitamins, getting worse when fresh milk is diluted.

[Comparative study of 3 different prophylactic programs in hemophiliac children].

Prophylaxis continues to be an area for discussion in the therapy of the hemophilic child. In fact, standard parameters are still not used in the evaluation of the efficacy of this treatment. At the Milan University Pediatric Clinic we have begun three different prophylactic programs with 52 children with ages ranging from 12 months to 14 years 7 months.

[Infantile angiodysplasias: diagnosis and therapy].

Three cases of angiodysplasias are reported. There are some problems still open concerning diagnostic and therapeutic approach. In this paper we try to correlate localisation, time of onset, size, aspect, histological features, evolution, side effects and hemodynamic problems with diagnosis, prognosis and therapy of childhood angiodysplasias mainly concerning cavernous, intracranial, visceral and lymphatic angiomas.