Publications by authors named "L Arzt-Gradwohl"
Article Synopsis
- Some people who have bad reactions to insect stings might have a problem with their mast cells, which can make their reactions worse and affect their treatment.
- A study looked at 1,319 people who needed treatment for bee or wasp stings and found that 21.6% had a specific marker (KIT p.D816V) that showed their mast cells were acting up, especially in those with severe reactions.
- The research also showed that having this marker along with another condition (HαT) made it even more likely for someone to have very bad reactions, highlighting the importance of testing and understanding these conditions for better treatment.
Influencing factors on the safety and effectiveness of venom immunotherapy.
J Investig Allergol Clin Immunol
November 2023
Background And Objective: The safety profile of venom immunotherapy (VIT) is a relevant issue and considerable differences in safety and efficacy of VIT have been reported. The primary aim of this study was to evaluate the safety of ACE inhibitors and beta-blockers during VIT, which has already been published. For a second analysis, data concerning premedication and venom preparations in relation to systemic adverse events (AE) during the up-dosing phase and the first year of the maintenance phase were evaluated as well as the outcome of field stings and sting challenges.
View Article and Find Full Text PDFInsect venom allergy is the most frequent cause of anaphylaxis in Europe and possibly worldwide. The majority of systemic allergic reactions after insect stings are caused by Hymenoptera, and among these, vespid genera induce most of the systemic sting reactions (SSR). Honey bees are the second leading cause of SSR.
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