Publications by authors named "L Arriero"
Is chemodenervation with incobotulinumtoxinA an alternative to invasive chronic anal fissure treatments?
BMC Gastroenterol
September 2024
Article Synopsis
- Botulinum toxin type A (incoBoNT/A) is effective in treating anal fissures (AFs) that haven't responded to other treatments, showing a healing rate of 83.9% after 2 years in a study with 49 patients.
- The treatment involved injecting the toxin into specific areas around the anal sphincter, resulting in significant reductions in anal resting pressure and pain perception over time, although there was a temporary increase in incontinence that resolved.
- The study suggests incoBoNT/A offers a safe, less invasive alternative to surgery for AF treatment, especially for patients unresponsive to ointment therapy, with only mild and temporary adverse events reported.