Publications by authors named "L Arathy Manohar"

Oral verrucous carcinoma is a form of well differentiated squamous cell carcinoma characterized by exophytic over growth. It is slow growing and locally invasive tumor occurring in 6 th and 7 th decade of life. Smoking and chewing tobacco is found to be the most common etiological factor of verrucous carcinoma although oral leukoplakia may act as a predisposing factor.

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Purpose: To biomechanically compare No. 2 polyblend suture with 2-mm polyblend tape in a bovine rotator cuff model as well as in isolation.

Methods: Ten paired bovine infraspinatus specimens were randomly assigned to simple suture fixation with either No.

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Background: Several biomechanical studies comparing open and arthroscopic rotator cuff repair methods have shown inferior performance of arthroscopic repairs. Suture anchor-augmented transosseous repairs and suture bridge repairs have shown superior biomechanical performance when compared with other methods, but these 2 repair methods have not been directly compared.

Hypothesis: There will be no difference in the biomechanical performance of the transosseous-suture anchor and suture bridge techniques.

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Background: Despite technical advances in rotator cuff surgery, recurrent or persistent defects in the repaired tendon continue to occur. Improved strength of sutures and suture anchors has resulted in the most common site of failure being the suture-tendon interface.

Hypothesis: The type of suture material used has a significant effect on the biomechanics of the suture-tendon interface.

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We use ab initio results to reparameterize a multi-reference semiempirical method to reproduce the ground and excited state potential energy surfaces (PESs) for the chromophore of Green Fluorescent Protein (GFP). The validity of the new parameter set is tested, and the new method is combined with a quantum mechanical/molecular mechanical (QM/MM) treatment so that it can be applied in the solution phase. Solvent effects on the energetics of the relevant conical intersections are explored.

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