Publications by authors named "L Appelman"

Objectives: The breast ultrasound trial (BUST) demonstrates a high negative predictive value of ultrasound for women presenting with focal breast complaints, suggesting a potential shift from mammography/digital breast tomosynthesis (DBT) to ultrasound as a primary imaging modality. This BUST side-study explored women's perspectives on adopting ultrasound as the primary diagnostic tool.

Methods: Twenty-nine female BUST participants (mean age = 48.

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Introduction: The high diagnostic accuracy of ultrasound opens possibilities to shift towards an initial ultrasound approach for the evaluation of focal breast complaints in women, with only additional DBT in case of unclear or suspicious ultrasound findings. As general practitioners (GPs) are important stakeholders in the diagnostic pathway, this study focuses on GPs perspective on ultrasound as primary diagnostic imaging test, as well as the GP referral process.

Methods: Sixteen Dutch GPs were interviewed on the referral process and their perceived barriers and facilitators of initial ultrasound diagnostics in women presenting with focal breast complaints.

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Background: Although DBT is the standard initial imaging modality for women with focal breast symptoms, the importance of ultrasound has grown rapidly in the past decades. Therefore, the Breast UltraSound Trial (BUST) focused on assessing the diagnostic value of ultrasound and digital breast tomosynthesis (DBT) for the evaluation of breast symptoms by reversing the order of breast imaging; first performing ultrasound followed by DBT. This side-study of the BUST evaluates patients' perceptions of ultrasound and DBT in a reversed setting.

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Article Synopsis
  • Breast complaints like pain, lumps, and nipple discharge are common reasons for patients to visit primary care or breast clinics, with some less common symptoms needing specific diagnostic methods.
  • Imaging the breast should be done by trained radiologists, using techniques like ultrasound, full-field digital mammography, and digital breast tomosynthesis based on the patient's age and symptoms.
  • It's crucial to accurately diagnose breast issues to identify potential malignancies while minimizing false positives and unnecessary procedures, ensuring a cost-effective and less anxiety-inducing process for patients.
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Owing to its high sensitivity, as concluded in the Breast UltraSound Trial (BUST), targeted ultrasound (US) now seems a promising accurate stand-alone modality for diagnostic evaluation of breast complaints. This approach implies omission of bilateral digital breast tomosynthesis (DBT) in women with clearly benign US findings. Within BUST, radiologists started with US followed by DBT.

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