Publications by authors named "L Antolini"
Article Synopsis
- Myeloproliferative neoplasms are disorders involving stem cells, where chronic inflammation plays a significant role in complications like blood clots, and the neutrophil-to-lymphocyte ratio (NLR) is becoming a potential prognostic tool for assessing these conditions.
- A study of 473 patients with essential thrombocythemia showed that a high NLR at diagnosis (≥4) increased the risk of both arterial and venous thrombotic events, alongside other factors such as diabetes and hypertension.
- The NLR is an accessible inflammatory marker that could be used alongside traditional cardiovascular risk assessments to identify patients at higher risk for thrombosis in essential thrombocythemia.
Introduction: Spinning Babies® procedures and the Rebozo technique have been recently implemented as additional interventions in laboring women with a fetus in occiput posterior position (OPP) to favor the rotation to an anterior position, which improve birth experience and health outcomes. Our study aimed to compare the probability of occurrence of persistent OPP (POPP) of the fetal head at the second stage of labor between retrospective and prospective cohorts and to assess associated sociodemographic, obstetric and intrapartum factors.
Methods: We conducted a combined prospective and retrospective cohort study including 1500 women giving birth in 2017 (retrospective cohort) and 779 between 15 May and 15 December 2023 (prospective cohort).
COVID-19 has a negative impact on the survival of respiratory patients, especially those with interstitial lung disease. This review aims to better understand the effect of COVID-19 on patients with idiopathic pulmonary fibrosis (IPF). A systematic search of MEDLINE, PubMed, Embase, and Scopus performed from December 2019 up to July 2024 identified relevant studies.
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- * The study evaluated 195 children and adolescents for various health measurements, including blood pressure and cholesterol levels, focusing on the potential role of Lp(a) in identifying those at risk.
- * Results indicated that 22.6% had elevated Lp(a) levels, primarily in normal-weight children, although a small percentage showed both high Lp(a) and LDL cholesterol levels, suggesting that most participants had normal lipoprotein profiles.
Impairment of Renal and Hematopoietic Stem/Progenitor Cell Compartments in Frailty Syndrome: Link With Oxidative Stress, Plasma Cytokine Profiles, and Nuclear DNA Damage.
J Gerontol A Biol Sci Med Sci
November 2024
Frailty is an age-related syndrome that drives multiple physiological system impairments in some older adults, and its pathophysiological mechanisms remain unclear. We evaluated whether frailty-related biological processes could impair stem cell compartments, specifically the renal stem compartment, given that kidney dysfunctions are frequent in frailty. A well-characterized in vitro nephrosphere model of human adult renal stem/progenitor cells has been instrumental to and was appropriate for verifying this hypothesis in our current research.
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