Publications by authors named "L Ambrosio"

Introduction: The majority of the studies on pulmonary rehabilitation (PR) in post-tuberculosis lung disease (PTLD) were from a single center, had a low sample size and/or did not allow a complete functional evaluation before and after PR program (PRP). The objective of this study was to evaluate if PTLD patients had benefits from PR in a large collaborating multicentre study conducted in reference centers in Brazil, Italy and France.

Methods: PTLD patients underwent a comprehensive 5-week PRP (Group 1), and were compared with non-rehabilitated patients (Group 2).

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Context: Both primary hyperparathyroidism (PHPT) and chronic hypoparathyroidism (HypoPT) are associated with the onset and development of cardiovascular diseases (CVDs). However, the molecular mechanisms underlying the effects of parathyroid disorders on endothelial dysfunction and platelet aggregation, two main determinants of CVDs, are not completely understood.

Objective: To evaluate the effects of PHPT and HypoPT on oxidative stress, endothelial and platelet function.

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Introduction: Knowledge translation from research to clinical practice can often be challenging, and practice modification patterns among surgeons may stem from a variety of sources, including personal experience, peer influence, ongoing education, and evolving research findings.

Research Question: This study aimed to investigate the adoption patterns amongst surgeons for newer innovations and to analyse the factors affecting the implementation of the same in clinical practice. We used the adoption of osteobiologics as a case example.

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Background: The continuous emergence of SARS-CoV-2 variants and subvariants poses significant public health challenges. The latest designated subvariant JN.1, with all its descendants, shows more than 30 mutations in the spike gene.

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Purpose: The rate of lumbar spine surgeries has increased and the postoperative course is influenced not only by physical but also psychological factors. Patients with pre-existing psychological disorders appear to be more likely to develop anxiety and depression, these factors could negatively affect pain perception, disability, and quality of life. A systematic review and metanalysis were performed to determinate which psychological factors impact on spinal postoperative clinical outcomes and how it can influence postoperative clinical outcomes in patients undergoing spinal surgery.

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