Association of multidimensional schizotypy with cognitive-behavioral disorganization in daily life: An experience sampling methodology study.

Schizotypy is a multidimensional construct that is composed of positive, negative, and disorganized dimensions. Historically, disorganized schizotypy, which involves disruptions in thoughts, speech, behavior, and affect, has been relatively understudied and less clearly operationalized than the other dimensions. The present study employed experience sampling methodology to examine the associations of positive, negative, and disorganized schizotypy, as measured by the Multidimensional Schizotypy Scale, with daily life experiences.

Bridging Gaps: Enhancing Sleep and Health Disparities in Latino Families with Young Adults with Autism Using a Culturally Adapted Intervention.

The present study examined the effects of a culturally adapted intervention, ¡Iniciando! la Adultez, on sleep and health-related quality of life (HRQoL) in Latino young adults with autism spectrum disorder (ASD) and their Spanish-speaking parents. The intervention targeted the transition to adulthood, a period associated with increased challenges in sleep and HRQoL, particularly for underserved Latino populations. Participants included 26 young adults and 38 parents who completed assessments at baseline and post-treatment.

Clinical and economic burden of varicella in pediatric patients hospitalized in four institutions in Guatemala.

Varicella presents a public health challenge in Guatemala, with limited evidence regarding its impact; vaccine is currently absent from the national immunization program. Generating local data on the economic and health burden can support immunization policies. This study describes the use of hospital resources, costs of care, clinical and demographic characteristics, and complications in children with varicella.

Deleterious coding variation associated with autism is consistent across populations, as exemplified by admixed Latin American populations.

The past decade has seen remarkable progress in identifying genes that, when impacted by deleterious coding variation, confer high risk for autism spectrum disorder (ASD), intellectual disability, and other developmental disorders. However, most underlying gene discovery efforts have focused on individuals of European ancestry, limiting insights into genetic risks across diverse populations. To help address this, the Genomics of Autism in Latin American Ancestries Consortium (GALA) was formed, presenting here the largest sequencing study of ASD in Latin American individuals (n>15,000).

Social issues in general practice - a survey assessing the interprofessional perspective of general practitioners and social workers regarding frequency, challenges, and needs.

Background: Health or illness and social issues cannot be viewed in isolation. Social problems can influence well-being and disease. General Practitioners (GPs) are requested to offer counselling opportunities to respond to the social issues of their patients adequately.