Publications by authors named "L Alonso-Pulpon"
Introduction: We conducted a study to determine the prevalence of structural heart disease in patients with CF, the characteristics of a cardiomyopathy not previously described in this population, and its possible relationship with nutritional deficiencies in CF.
Methods: We studied 3 CMP CF patients referred for heart-lung transplantation and a prospective series of 120 adult CF patients. All patients underwent a clinical examination, blood tests including levels of vitamins and trace elements, and echocardiography with evaluation of myocardial strain.
Background: Parathormone (PTH) is a component of the Mineral Metabolism (MM) system that has been shown recently to add prognostic value in pts. with stable coronary artery disease (SCAD) and average renal function. However, the influence of renal function on the prognostic role of PTH in pts.
View Article and Find Full Text PDFAims: There are controversial data on the ability of the components of mineral metabolism (vitamin D, phosphate, parathormone [PTH], fibroblast growth factor-23 [FGF23], and klotho) to predict cardiovascular events. In addition, it is unknown whether they add any prognostic value to other well-known biomarkers.
Methods And Results: In 969 stable coronary patients, we determined plasma levels of all the aforementioned components of mineral metabolism with a complete set of clinical and biochemical variables, including N-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitivity troponin I (hs-TnI), and high-sensitivity C-reactive protein.
Article Synopsis
- The study focuses on improving outcomes for patients with cardiogenic shock (CS), particularly those requiring mechanical circulatory support (MCS), by analyzing a care program implemented by a multidisciplinary team in a regional hospital network from 2014 to 2019.
- A total of 130 patients were examined, with a majority being middle-aged men; most cases were due to heart failure or myocardial infarction, and 81% of patients used MCS, primarily extracorporeal membrane oxygenation (ECMO).
- The program achieved a 57% survival rate to discharge, suggesting that a coordinated approach with specialized teams significantly benefits patients in critical conditions like refractory CS.
Article Synopsis
- Cardiac amyloidosis (CA) is caused by amyloid fiber buildup in the heart, primarily from light chains (AL) or transthyretin (ATTR), and this study aimed to describe its diagnosis and treatment outcomes in a Spanish hospital.
- The study involved 180 patients diagnosed with CA, where the majority were diagnosed with ATTR, showing that heart failure was the most common symptom, but AL patients had higher mortality rates.
- The research highlighted significant diagnostic delays for ATTR patients and identified key mortality predictors, emphasizing the need for improved early detection and treatment strategies for CA.