Publications by authors named "L Allende Honorato"

Unlabelled: is an emerging fungal pathogen notable for its resistance to multiple antifungals and ability to survive in various environments. Understanding the interactions between and environmental protozoa, such as could provide insights into fungal adaptability and pathogenicity. Two isolates (MMC1 and MMC2) were co-cultured with to examine interaction dynamics, survival, stress responses, growth, virulence, biofilm formation, and antifungal susceptibility.

View Article and Find Full Text PDF

The lower female reproductive tract (FRT) hosts a complex microbial environment, including eukaryotic and prokaryotic viruses (the virome), whose roles in health and disease are not fully understood. This review consolidates findings on FRT virome composition, revealing the presence of various viral families and noting significant gaps in knowledge. Understanding interactions between the virome, microbiome, and immune system will provide novel insights for preventing and managing lower genital tract disorders.

View Article and Find Full Text PDF
Article Synopsis
  • A CRESS-DNA virus, primarily found in fecal samples from vertebrates, was examined in human vaginal samples for its presence.
  • Viral metagenomics was conducted on samples from 28 healthy women in NYC, with some providing duplicates over a 12-21 day span.
  • The study found that one individual had continuous detection of the CRESS-DNA virus over a twelve-day period, indicating it can persist in the human vagina.
View Article and Find Full Text PDF

The urgency surrounding as a public health threat is highlighted by both the Center for Disease Control (CDC) and World Health Organization (WHO) that categorized this species as a priority fungal pathogen. Given the current limitations of antifungal therapy for , particularly due to its multiple resistance to the current antifungals, the identification of new drugs is of paramount importance. Some alkaloids abundant in the venom of the red invasive fire ant (), known as solenopsins, have garnered attention as potent inhibitors of bacterial biofilms, and there are no studies demonstrating such effects against fungal pathogens.

View Article and Find Full Text PDF

We demonstrated the antinociceptive and anti-inflammatory effects of the ethyl acetate leaf extract of (Jacq.) Sargent (EAECi) in mice. The antioxidant activity of EAECi and its phytoconstituents was also investigated.

View Article and Find Full Text PDF