Publications by authors named "L Alfonsi"
: Home parenteral nutrition (HPN) is a life-saving treatment for patients affected by chronic intestinal failure (CIF). Both this clinical condition and its therapy require radical lifestyle modifications, affecting life quality and psychological balance in patients as well as family members. Patient psychological burden has rarely been taken into consideration, not to mention that of caregivers.
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- Gestational diabetes mellitus (GDM) is linked to both immediate obstetric issues and long-term cardiovascular risks, but its effects on platelet function have been underexplored compared to type-2 diabetes.
- The study compared 23 women with GDM to 23 healthy pregnant women, measuring various aspects of platelet reactivity and endothelial function at different stages of pregnancy and postpartum.
- Results indicated that women with GDM had increased platelet hyperreactivity and activation, especially towards the end of pregnancy, with some abnormalities persisting up to 8 weeks after delivery, along with signs of endothelial dysfunction.
Background: Partial enteral nutrition (PEN) is a well-established treatment for children with Crohn's disease (CD). However, its efficacy in adults with CD remains uncertain. We aimed to assess the effectiveness of PEN as an add-on to escalated biological therapy in adults with CD who have lost response to biologics.
View Article and Find Full Text PDFWe study how human capital and economic conditions causally affect the choice of religious denomination. We utilize a longitudinal dataset monitoring the religious history of more than 5,000 Kenyans over twenty years, in tandem with a randomized experiment (deworming) that has exogenously boosted education and living standards. The main finding is that the program reduces the likelihood of membership in a Pentecostal denomination up to 20 years later when respondents are in their mid-thirties, while there is a comparable increase in membership in traditional Christian denominations.
View Article and Find Full Text PDFIntroduction: The goal of this quality improvement project was to improve timing, communication, and continued care for pediatric patients who present to the emergency department at a Level I pediatric trauma center and require inpatient admission.
Methods: Using continuous improvement methodology, a patient flow process was created to improve the throughput of pediatric patients requiring inpatient admission from the emergency department, aimed at decreasing the time from decision to admit to actual admission. The new workflow included ED and inpatient nursing collaboration, with nursing leaders coordinating patient transfer.