Acute physical exercise and ambulatory blood pressure in resistant hypertension.

Objectives: The effects of acute physical exercise in patients with resistant hypertension remain largely unexplored compared with hypertensive patients in general. We assessed the short-term effects of acute moderate-intensity (MICE) and high-intensity interval exercise (HIIE) on the clinic (BP) and 24-h ambulatory blood pressure (ABP) of patients with resistant hypertension.

Methods: Using a crossover randomized controlled design, 10 participants (56 ± 7 years) with resistant hypertension performed three experimental sessions: MICE, HIIE, and control.

Intrasession Caffeine Intake and Cycling Performance After Accumulated Work: A Field-Based Study.

Background: Preexercise caffeine intake has proven to exert ergogenic effects on cycling performance. However, whether these benefits are also observed under fatigue conditions remains largely unexplored. We aimed to assess the effect of caffeine ingested during prolonged cycling on subsequent time-trial performance in trained cyclists.

Off- and On-Bike Resistance Training in Cyclists: A Randomized Controlled Trial.

Purpose: This study compared the effects of off- and on-bike resistance training (RT) on endurance cycling performance as well as muscle strength, power, and structure.

Methods: Well-trained male cyclists were randomly assigned to incorporate two sessions/week of off-bike (full squats, n = 12) or on-bike (all-out efforts performed against very high resistances and thus at very low cadences, n = 12) RT during 10 wk, with all RT-related variables (number of sessions, sets, and repetitions, duration of recovery periods, and relative loads [70% of one-repetition maximum]) matched between the two groups. A third, control group ( n = 13), did not receive any RT stimulus, but all groups completed a cycling training regime of the same volume and intensity.

Exercise Intolerance in McArdle Disease: A Role for Cardiac Impairment? A Preliminary Study in Humans and Mice.

Introduction: Whether cardiac impairment can be fully discarded in McArdle disease-the paradigm of "exercise intolerance," caused by inherited deficiency of the skeletal muscle-specific glycogen phosphorylase isoform ("myophosphorylase")-remains to be determined.

Methods: Eight patients with McArdle disease and seven age/sex-matched controls performed a 15-min moderate, constant-load cycle-ergometer exercise bout followed by a maximal ramp test. Electrocardiographic and two-dimensional transthoracic (for cardiac dimension's assessment) and speckle tracking (for left ventricular global longitudinal strain (GLS) assessments) echocardiographic evaluations were performed at baseline.

Intensity Matters: Effect of Different Work-Matched Efforts on Subsequent Performance in Cyclists.

Purpose: To assess the effect of 2 work-matched efforts of different intensities on subsequent performance in well-trained cyclists.

Methods: The present study followed a randomized controlled crossover design. Twelve competitive junior cyclists volunteered to participate (age, 17 [1] y; maximum oxygen uptake, 71.