Publications by authors named "L Albornoz"

Sarcoptic mange or scabies is a contagious parasitic skin disease that affects a wide range of domestic and wildlife species. A cross-sectional study was carried out to determine the prevalence, molecular identification, and characteristics of sarcoptic mange in vicuñas. A total of 3,274 vicuñas were examined.

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The asymptomatic population's role in COVID-19 transmission poses challenges for control efforts. Pregnant women are susceptible to severe manifestations, increasing maternal and perinatal morbidity and mortality. This study describes the clinical characteristics, maternal and fetal outcomes, and our experience in universal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) screening of pregnant women admitted to a high-complexity obstetric unit in Latin America.

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Article Synopsis
  • Pregnant women face increased risks of severe complications from COVID-19, which may be linked to unique changes in their immune response during pregnancy.
  • A study analyzed plasma samples from 72 pregnant and 52 non-pregnant individuals, revealing differences in protein expression that reflect disease severity and indicate a tailored immune response in pregnant women.
  • The research highlights how pregnant individuals show milder proteomic changes during COVID-19, potentially protecting the fetus, while non-pregnant individuals mount a stronger response against the virus, underscoring distinct immune mechanisms at play.
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Pregnant women are at greater risk of adverse outcomes, including mortality, as well as obstetrical complications resulting from COVID-19. However, pregnancy-specific changes that underlie such worsened outcomes remain unclear. Herein, we profiled the plasma proteome of pregnant and non-pregnant COVID-19 patients and controls and showed alterations that display a dose-response relationship with disease severity; yet, such proteomic perturbations are dampened during pregnancy.

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