Publications by authors named "L Affengruber"

Background: Systematic reviews (SRs) are time-consuming and labor-intensive to perform. With the growing number of scientific publications, the SR development process becomes even more laborious. This is problematic because timely SR evidence is essential for decision-making in evidence-based healthcare and policymaking.

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Background And Objective: Rapid reviews have gained popularity as a pragmatic approach to synthesize evidence in a timely manner to inform decision-making in healthcare. This article provides an overview of the key concepts and methodological considerations in conducting rapid reviews, drawing from a series of recently published guidance papers by the Cochrane Rapid Reviews Methods Group.

Study Design And Setting: We discuss the definition, characteristics, and potential applications of rapid reviews and the trade-offs between speed and rigor.

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This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RRs) use modified systematic review methods to accelerate the review process while maintaining systematic, transparent and reproducible methods. This paper guides how to use supportive software for RRs.

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Background: Primary care patients and clinicians may prefer alternative options to second-generation antidepressants for major depressive disorder (MDD).

Purpose: To compare the benefits and harms of nonpharmacologic treatments with second-generation antidepressants as first-step interventions for acute MDD, and to compare second-step treatment strategies for patients who did not achieve remission after an initial attempt with antidepressants.

Data Sources: English-language studies from several electronic databases from 1 January 1990 to 8 August 2022, trial registries, gray literature databases, and reference lists to identify unpublished research.

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Background: Developers of clinical practice guidelines need to take patient values and preferences into consideration when weighing benefits and harms of treatment options for depressive disorder.

Purpose: To assess patient values and preferences regarding pharmacologic and nonpharmacologic treatments of depressive disorder.

Data Sources: MEDLINE (Ovid) and PsycINFO (EBSCO) were searched for eligible studies published from 1 January 2014 to 30 November 2022.

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