Ruthenaelectro-catalyzed C-H phosphorylation: to position-selectivity switch.

The position-selective C-H bond activation of arenes has long been a challenging topic. Herein, we report an expedient ruthenium-electrocatalyzed site-selective -C-H phosphorylation of arenes driven by electrochemical hydrogen evolution reaction (HER), avoiding stoichiometric amounts of chemical redox-waste products. This strategy paved the way to achieve unprecedented ruthenaelectro-catalyzed -C-H phosphorylation with excellent levels of site-selectivity.

Visible light-induced ruthenium(ii)-catalyzed hydroarylation of unactivated olefins.

Hydroarylation reactions have emerged as a valuable tool for the direct functionalization of C-H bonds with ideal atom economy. However, common catalytic variants for these transformations largely require harsh reaction conditions, which often translate into reduced selectivites. In contrast, we herein report on a photo-induced hydroarylation of unactivated olefins at room temperature employing a readily available ruthenium(ii) catalyst.

Metallaelectro-catalyzed alkyne annulations C-H activations for sustainable heterocycle syntheses.

Alkyne annulation represents a versatile and powerful strategy for the assembly of structurally complex compounds. Recent advances successfully enabled electrocatalytic alkyne annulations, significantly expanding the potential applications of this promising technique towards sustainable synthesis. The metallaelectro-catalyzed C-H activation/annulation stands out as a highly efficient approach that leverages electricity, combining the benefits of electrosynthesis with the power of transition-metal catalyzed C-H activation.

Medical Consultation and Comanagement.

Hospital medicine grew rapidly, creating a group of providers excelling at providing high-value and high-quality care. Consultative medicine aims to answer specific questions regarding aspects of a patient's care. Comanagement models initially evolved as surgical services began operating on increasingly medically complex patients.

Copper(0)-Catalyzed Reductive Coupling of Disulfurating Reagents and (Hetero)aryl/Alkyl Halides.

Herein, we reported a copper(0)-catalyzed reductive coupling of disulfurating reagents and (hetero)aryl/alkyl halides. Copper(0) can be directly inserted into tetrasulfide and then undergoes reductive coupling with (hetero)aryl Iodides to construct disulfide. The method features the unprecedented use of copper(0)-catalyzed disulfurating reagents (tetrasulfides) in cross-coupling chemistry and is convenient with broad substrate scopes, even applicable to different halogenated hydrocarbons.