Publications by authors named "L Abrahao"

Aim: To analyse the effects of an individualized telehealth home programme on the performance of functional goals of children and adolescents with cerebral palsy (CP) during the COVID-19 pandemic.

Method: A prospective single-group intervention study with children/adolescents with CP (n = 144; median age = 92 months [Q = 44.0, Q = 148.

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Background: High-resolution impedance manometry (HRIM) evaluates esophageal peristalsis and bolus transit. We used esophageal impedance integral (EII), the ratio between bolus presence before and after an expected peristaltic wave, to evaluate predictors of bolus transit.

Methods: From HRIM studies performed on 61 healthy volunteers (median age 27 years, 48%F), standard metrics were extracted from each of 10 supine water swallows: distal contractile integral (DCI, mmHg cm s), integrated relaxation pressure (IRP, mmHg), and breaks in peristaltic integrity (cm, using 20 mmHg isobaric contour).

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Article Synopsis
  • * The research analyzed HRM studies from various global motility centers, finding that 74.6% of participants had normal results, with ineffective esophageal motility (IEM) being the most common abnormal finding (15.1%).
  • * The study concluded that motor abnormalities are rare in healthy individuals, with IEM being the primary issue, and noted that thresholds for HRM measurements differ depending on the HRM system and whether the patient was upright or supine.
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Background: Esophagogastric junction contractile integral (EGJ-CI) and EGJ morphology are high-resolution manometry (HRM) metrics that assess EGJ barrier function. Normative data standardized across world regions and HRM manufacturers are limited.

Methods: Our aim was to determine normative EGJ metrics in a large international cohort of healthy volunteers undergoing HRM (Medtronic, Laborie, and Diversatek software) acquired from 16 countries in four world regions.

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