Publications by authors named "L A del Rio"

This prospective case-control study explored the association between urinary magnesium levels and acute urinary retention (AUR) in individuals presenting to the emergency department. Forty-six participants, comprising 23 cases and 23 age- and sex-matched controls, underwent urine analysis for magnesium, calcium, and creatinine concentrations. The exclusion criteria mitigated potential confounding factors.

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  • - The study evaluated the safety and effectiveness of PuraStat, a topical hemostatic agent, for treating active gastrointestinal bleeding and preventing bleeding in patients undergoing endoscopic procedures.
  • - Data from 401 patients across ten Italian centers showed PuraStat achieved hemostasis in nearly all cases of active bleeding (98.9%) and had a low follow-up bleeding rate (3.9%) for preventive uses.
  • - No adverse events related to PuraStat were reported, indicating it is a safe option that could be used for broader applications than currently recommended.
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  • Strategies to enhance natural killer (NK) cell responses against cancer include using tumor-targeting antibodies, NK cell engagers, and adopting NK cells from healthy donors.
  • KIR2DS2, an activating receptor on NK cells, is linked to better cancer outcomes in healthy individuals, but its optimal use in therapy is uncertain.
  • Research found that KIR2DS2+ NK cells from cancer patients respond better to antibodies than KIR2DS2- cells, but the effectiveness of KIR2DS2+ NK cells from healthy donors decreases after expansion needed for therapeutic use.
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In ovine populations, the enzootic nature of () is attributed to its capacity to establish persistent intracellular infections, which necessitate a cellular immune response mediated by interferon-gamma (IFN-) for effective resolution. In both natural hosts and murine models, interleukin-10 (IL-10) has been demonstrated to modulate the cellular immune response crucial for the eradication of . During gestation, it has also been shown to play a role in preventing inflammatory damage to gestational tissues and foetal loss through the downregulation of pro-inflammatory cytokines.

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