[When will the new tuberculosis vaccine appear?].

The problem of tuberculosis prophylaxis remains actual for many countries of the world including Russia. The search of candidates for substitution of the only authorized BCG vaccine has been ongoing for some time, because it does not prevent reactivation of the causative agent in the latent stage and causes generalized BCG-infection in individuals with pronounced immune deficiency. In October 2013 in Lille at the European Congress "World Vaccine 2013" results of multi-year projects and trials of around 40 novel tuberculosis vaccine candidates were presented.

[IgM, IgG and IgG subclass antibodies to herpes simplex virus in persons of different ages].

IgM, IgG antibodies to herpes simplex virus and their subclases were investigated in 565 subjects of different age tested at virological laboratories of St. Petersburg in 1996-1997. The majority of these subjects had a history of herpes infection and 21.

[Frequency of acute cytomegalovirus infections among people of differing age groups].

The incidence of cytomegalovirus (CMV) infection was assessed from the presence of anti-CMV IgM in the sera of 1312 children of different age and 250 adults by the Labsystems enzyme immunoassay kit. CMV-specific IgM are rare in newborns (1.3%), but their incidence increases to 5% during the first year of life.

[Development and application of immunoenzyme test-system for the diagnosis of acute cytomegalovirus infection].

Enzyme immunoassay for the detection of IgM antibodies to human cytomegalovirus (CMV) has been developed. Use of horseradish peroxidase conjugated monoclonal antibodies to human IgM helped create a highly specific test system. The rheumatoid factor was removed from the serum by staphylococcal reagent containing protein A.

[A comparative study of the protective properties of live recombinant and inactivated influenza vaccines made from strain A/Philippines/2/82 (H3N2) in 8- to 15-year-old children].

A limited controlled comparative study for the evaluation of the epidemiological efficacy of live recombinant and inactivated virion vaccines from A/Philippines/2/82-like strains of influenza A (H3N2) virus was carried out in schoolchildren of 8 to 15 years of age. During the influenza epidemic of 1987-1988 caused by influenza A/Sichuan/2/87 (H3N2)-like strains and by influenza B virus in 8.2-17% of cases, a statistically significant efficacy index for live influenza vaccine was 1.