Publications by authors named "L A Winslow"
The Cryogenic Underground Observatory for Rare Events (CUORE) is a detector array comprised by 988 5 cm×5 cm×5 cm TeO_{2} crystals held below 20 mK, primarily searching for neutrinoless double-beta decay in ^{130}Te. Unprecedented in size among cryogenic calorimetric experiments, CUORE provides a promising setting for the study of exotic throughgoing particles. Using the first tonne year of CUORE's exposure, we perform a search for hypothesized fractionally charged particles (FCPs), which are well-motivated by various standard model extensions and would have suppressed interactions with matter.
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- - The study aims to compare the retinal and choroidal structures and microvascular health between individuals with mild to moderate traumatic brain injury (TBI) and healthy controls using optical coherence tomography (OCT) and OCT angiography (OCTA).
- - Results show significant reductions in certain OCTA parameters, including the foveal avascular zone circularity and macular vessel density in TBI patients, particularly those also experiencing posttraumatic stress disorder.
- - The choroidal vascularity index demonstrated potential for indicating the severity of TBI, suggesting that further research could utilize OCT and OCTA as non-invasive tools to monitor retinal and choroidal changes in TBI patients.
Article Synopsis
- Frontotemporal dementia (FTD) is a neurodegenerative disorder affecting brain areas linked to cognition and personality, and this study aimed to explore retinal and choroidal changes in FTD patients compared to cognitively normal individuals using specialized imaging techniques.
- The study involved analyzing various retinal imaging parameters in 19 FTD patients and 48 control participants, using methods like optical coherence tomography (OCT) and OCT angiography (OCTA) to assess differences in retinal tissue and blood flow.
- Results indicated significant reductions in macular perfusion density and vessel density in FTD patients, suggesting that retinal changes could serve as potential biomarkers for early detection of FTD, warranting further research using noninvasive imaging techniques.