Unusual Co-Occurrence of Multiple Myeloma and AML in a Patient With Germline CEBPA Variant. Expanding the Spectrum of Hereditary Hematologic Malignancies.

Timeline and genetic analysis of a 55-year-old female with a family history of gastric cancer and multiple myeloma, who was diagnosed with AML and a germline CEBPA variant.

Quantifying HLA Mismatches at Epitope Level in Haplo-HSCT: Impact in the Outcome in Strategies Using PTCy.

Haploidentical haematopoietic stem cell transplantation (haplo-HSCT) is one of the most effective therapies for treating malignant haematological disorders. However, HLA disparities are significant barriers to the success of this process since they increase the risk of graft versus host disease (GvHD). HLA disparities quantification could help to anticipate the probability and degree of GvHD, but the best tool for such quantification remains a challenge.

The Field Assessment of Quiescent Egg Populations of and during the Dry Season in Tapachula, Chiapas, Mexico, and Its Potential Impact on Vector Control Strategies.

Although integrated management and control programs implement intense control measures for adult, pupal, larval, and breeding sites during outbreaks, there is a lack of studies to understand the role of the vector egg stage in disease dynamics. This study aimed to assess the dry season quiescent and egg populations in houses and backyards in Tapachula, southern Mexico. Two hundred and fifty ovitraps were placed in 125 homes in the Las Americas neighborhood.

Enhanced Electrochemical Detection of Nonelectroactive Compounds Based on Surface Supramolecular Interactions on Chevron-like Graphene Nanoribbons Modified through Click Chemistry.

In this study, we have developed a nanostructured electrochemical sensor based on modified graphene nanoribbons tailored for the analysis of nonelectroactive compounds via a surface competitive assay. Stigmasterol, a nonelectroactive phytosterol, was selected as a representative case. Chevron-like graphene nanoribbons, chemically synthesized, were immobilized onto glassy carbon electrodes and covalently functionalized to allow the on-surface formation of a supramolecular complex.