Measurements for certification of chlortetracycline reference materials within the European Union Standards, Measurements and Testing programme.

The experimental design of a material certification programme is described. The matrix reference materials (RMs) comprised chlortetracycline (CTC)-containing and CTC-free lyophilised porcine liver, kidney and muscle produced under the European Commission's Standards Measurements and Testing (SMT) programme. The aim of the certification programme was to determine accurately and precisely the concentration of CTC and 4-epi-chlortetracycline (epi-CTC) contained in the RMs.

Posterior subluxations of the medial and lateral tibiofemoral compartments. An in vitro ligament sectioning study in cadaveric knees.

We report for the first time the abnormal increases in posterior subluxation of the medial and lateral tibial plateaus after sectioning the posterolateral structures and posterior cruciate ligament. We applied specific forces and moments to the knees of seven cadaveric whole lower limbs and measured the position of the tibia at which the ligaments and the geometry of the joint limited motion. Removal of only the posterolateral structures resulted in an average increase in posterior translation of the lateral tibial plateau of 8.

Reproducibility of the knee signature system.

To assess trial-to-trial, installation-to-installation, and day-to-day effects of the Knee Signature System, we studied anterior/posterior translation measurements in six normal subjects. The protocol consisted of testing both knees on 6 days with three installations per day and three trials per installation. We recorded anterior, posterior, and total anterior/posterior translation at +/- 20 and +/- 40 pounds of force at 30 degrees of flexion.