Publications by authors named "L A Tibbles"
Background: Few studies have assessed outcomes in transplant recipients with failing grafts as most studies have focused on outcomes after graft loss.
Objective: To determine whether renal function declines faster in kidney transplant recipients with a failing graft than in people with chronic kidney disease of their native kidneys.
Design: Retrospective cohort study.
Article Synopsis
- - A study compared medication adherence between male and female transplant recipients for kidney, liver, and heart organs, using a self-report tool and tacrolimus level measurements over 6 months.
- - Males self-reported lower adherence but showed higher adherence based on tacrolimus levels; females reported better adherence but had higher variability in medication levels.
- - Findings suggest that social desirability bias might explain better self-reported adherence in females, while metabolic differences could account for variability, with no significant differences based on organ type.
Background: In controlled donation after circulatory determination of death (DCD), it is common to administer premortem heparin to potential donors. This practice remains controversial because there is limited evidence for it and there is the possibility of inducing hemorrhage. To our knowledge, no previous studies have assessed the effects of heparin timing and dose on graft function.
View Article and Find Full Text PDFBackground: Patients with kidney transplant failure have a high risk of hospitalization and death due to infection. The optimal use of immunosuppressants after transplant failure remains uncertain and clinical practice varies widely.
Methods: This prospective cohort study enrolled patients within 21 days of starting dialysis after transplant failure in 16 Canadian centers.