Publications by authors named "L A Tell"
Background: Psittacines (parrots and their allies) are kept under human care as companion animals, live exhibit specimens in zoological institutions and occasionally as research subjects. Cutaneous disorders such as feather destructive behaviour (FDB) and pododermatitis are commonly noted in clinical reviews, case reports and text book chapters.
Hypothesis/objectives: To document the type, signalment associations and prevalence of cutaneous disorders in a large number of captive psittacines in an academic referral teaching hospital population.
Flunixin meglumine is a nonsteroidal anti-inflammatory drug (NSAID). Banamine® Transdermal is a pour-on formulation of flunixin approved for pain control in beef and dairy cattle, but not for calves and some classes of dairy cattle or swine. Violative flunixin residues in edible tissues in cattle and swine have been reported and are usually attributed to non-compliant drug use or failure to observe an appropriate withdrawal time.
View Article and Find Full Text PDFFlorfenicol is a broad-spectrum and bacteriostatic antibiotic with a time-dependent killing action. It is commonly used to treat respiratory diseases in goats in an extra-label manner. This study aimed to determine the plasma pharmacokinetics and milk residue depletion profiles and calculate the milk withdrawal interval (WDI) of florfenicol and its main metabolite florfenicol amine in lactating goats.
View Article and Find Full Text PDFArticle Synopsis
- Plasma half-life is important for estimating withdrawal periods of drugs in food animals to ensure food safety.
- This study created a QSAR model using machine learning algorithms to predict plasma half-lives for drugs in cattle, chickens, goats, sheep, swine, and turkeys, utilizing data from FARAD.
- The deep neural network (DNN) algorithm showed the best prediction performance, achieving strong accuracy and leading to the development of a user-friendly web dashboard for broader scientific use.
Article Synopsis
- The study investigates the safe withdrawal interval (WDI) for fenbendazole in pheasants, as its use is considered extra-label in the U.S.
- Pheasants received fenbendazole medicated feed for 7 days, with tissue samples analyzed to determine drug metabolism and residue levels.
- Results indicate a maximum WDI of 153 hours for certain muscles, establishing fenbendazole sulfoxide as a key residue marker in pheasant liver, supporting safe food practices.