Publications by authors named "L A Tapondjou"

Article Synopsis
  • - A new saponin called diosgeninoside and a new fatty acid named betacic acid were discovered alongside six known compounds in a methanolic extract.
  • - The chemical structures of these compounds were determined using 1D and 2D NMR spectrometry and other methods.
  • - Both the methanolic extract and one of its fractions demonstrated moderate antibacterial activity against specific bacteria, with minimum inhibitory concentrations (MIC) measured at 128 µg/mL and 64 µg/mL for certain compounds.
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Article Synopsis
  • Four new triterpenoid saponins (manniosides G, H, I, and J) were identified from the leaves of a plant, alongside several known compounds.* -
  • Their structures were determined using advanced techniques like NMR analysis and mass spectrometry.* -
  • The extracts and some isolated compounds were tested for antibacterial properties but showed no significant antioxidant activity.*
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The genus is a rich source of physiologically active secondary metabolites, including a novel compound named 21-methylene-24-ethylidene lophenol, alongside 15 known compounds. These compounds were characterized using different spectroscopic techniques. They exhibited promising antimicrobial activity, particularly against bacteria causing gastrointestinal infections.

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Five unusual alkaloids featuring a pyrrolo[1,2-a]quinolone skeleton (pyrroloquinolones B-F, 1-5) were isolated from the ethanol extract of the whole plant of Vernonia glabra (Steetz) Vatke, along with sixteen known compounds. Their structures were established by means of spectroscopic (1D and 2D NMR, UV, IR, and ECD) and high resolution mass spectrometric techniques as well as by comparison of their spectroscopic data with those reported in the literature. The ethanol extract and some isolated compounds were assessed for their antibacterial activity against four bacterial strains.

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Article Synopsis
  • A new phenolic glucoside was isolated from the methanol extract of leaves, alongside fifteen known secondary metabolites with potential health benefits.
  • The structures of these compounds were determined using 1D and 2D NMR analysis and mass spectrometry.
  • The extracts and isolated compounds were tested for antibacterial activity, showing that some were highly effective against certain bacteria, while others had moderate activity.
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