Publications by authors named "L A Sumption"
Prenatal health behaviours as predictors of human placental lactogen levels.
Front Endocrinol (Lausanne)
September 2022
Article Synopsis
- Placental lactogen (hPL) is vital for pregnancy, influencing maternal adaptation and linked to infant birth weight and maternal mental health.
- * A study using data from the Grown in Wales cohort found prenatal smoking and a Health Conscious diet were initially associated with hPL levels, but only the diet maintained significance when adjusting for BMI and other factors.
- * Higher hPL levels were connected to increased custom birthweight centiles and a greater likelihood of delivering larger infants, emphasizing the importance of healthy dietary choices during pregnancy, particularly for women with a healthy BMI.
Altered serum levels of brain-derived neurotrophic factor (BDNF) are consistently linked with neurological disorders. BDNF is also increasingly implicated in the pathogenesis of neurodevelopmental disorders, particularly those found more frequently in males. At birth, male infants naturally have significantly lower serum BDNF levels (∼10-20% lower than females), which may render them more vulnerable to neurodevelopmental disorders.
View Article and Find Full Text PDFBrain-derived neurotrophic factor (BDNF) plays crucial roles in brain function. Numerous studies report alterations in BDNF levels in human serum in various neurological conditions, including mood disorders such as depression. However, little is known about BDNF levels in the blood during pregnancy.
View Article and Find Full Text PDFRisk factors for excessive gestational weight gain in a UK population: a biopsychosocial model approach.
BMC Pregnancy Childbirth
January 2021
Background: Gestational weight gain (GWG) can have implications for the health of both mother and child. However, the contributing factors remain unclear. Despite the advantages of using a biopsychosocial approach, this approach has not been applied to study GWG in the UK.
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