Bayesian Analysis of Censored Linear Mixed-Effects Models for Heavy-Tailed Irregularly Observed Repeated Measures.

The use of mixed-effect models to understand the evolution of the human immunodeficiency virus (HIV) and the progression of acquired immune deficiency syndrome (AIDS) has been the cornerstone of longitudinal data analysis in recent years. However, data from HIV/AIDS clinical trials have several complexities. Some of the most common recurrences are related to the situation where the HIV viral load can be undetectable, and the measures of the patient can be registered irregularly due to some problems in the data collection.

Cardiac Hemodynamics, Tissue Oxygenation, and Functional Capacity in Post-COVID-19 Patients.

: This study aimed to evaluate and compare the functional capacity of post-COVID-19 patients with a control group and analyze cardiac hemodynamics and muscle tissue oxygenation responses during assessment protocols in both groups. : A cross-sectional study was conducted involving patients with COVID-19 and a control group who were all aged ≥18 years. Participants underwent two functional capacity tests: the one-minute sit-stand test (1-STS) and the six-minute walk test (6MWT).

MITOCDNB DECREASES PLATELET ACTIVATION THROUGH ITS SELECTIVE ACTION ON MITOCHONDRIAL THIOREDOXIN REDUCTASE.

Platelet inhibition is a fundamental objective to prevent and treat thrombus formation. Platelet activation depends on mitochondrial function. This study aims to identify a new mitochondria-targeting compound with antiplatelet activity at safe concentrations in vitro.

Exploring the phytoremediation potential of plant species in soils impacted by gold mining in Northern Colombia.

Contamination of soils with toxic metals poses significant threats to human health and ecosystems. Plant-based remediation strategies can play a vital role in mitigating these risks, and the use of plants as a remediation strategy can help reduce these risks. In this study, we investigate the remediation potential of native plants in accumulating and translocating metal(loid)s at a Colombian site impacted by gold mining.