[Concentration of light hydrocarbons in exhaled air depending on the risk factors of metabolic disorder].

In this study we investigated the effect of risk factors of metabolic syndrome on the content of light hydrocarbons (C2-C3) in exhaled air. We used a gas chromatograph with a short multi-channel column. As a result, sex differences in concentrations of light hydrocarbons presented in exhaled air were found.

[Insulin-glucose parameters in healthy women and patients with arterial hypertension and ischemic heart disease in dependence on age and follicle-stimulating hormone levels].

Insulin-glucose parameters in healthy women do not significantly change with changes of functional state of ovaries. Women with hypertension and normal levels of glycemia have significantly higher values of basal insulinemia and HOMA-R index reflecting presence of moderate insulin resistance degree of which is more pronounced in middle aged patients. In women with documented ischemic heart disease values of basal insulinemia, HOMA-R index, and glycemia are comparable with those in patients with hypertension and follicle-stimulating hormone level above 30 IE/l and significantly differ from corresponding parameters in healthy women in peri- and postmenopause.

[Current views about the role of purin metabolism disorders in patients with arterial hypertension and losartan potentialities].

The analysis of correlation between cardiovascular diseases and hyperuricaemia as a component of methabolic syndrome has been performed; the emphasis has been done on predominant mechanism of its development -- reduction of renal clearance. The need for primary prophylaxis of stroke with a help of safe metabolically antihypertensive therapy has been substantiated. The results of secondary analysis of LIFE study represented its results on effective primary prophylaxis of stroke depending on the dynamic of serum uric acid levels taking into account uricosuric effect of losartan have been discussed.

[Hormone-producing function of the ovaries in young and middle-aged women with arterial hypertension and coronary heart disease].

The study demonstrates that arterial hypertension itself, judging by main anthropometric variables such as body weight index and waist to hip ratio, together with the estrogen-producing function of the ovaries, evaluated by measuring follicle-stimulating hormone levels, contributes substantially to the forming of abdominal obesity in normo- and hypertensive women. All the above confirms close correlation between hemodynamic and metabolic disturbances which eventually result in coronary heart disease in young and middle-aged women.