Publications by authors named "L A Pino"

The Age-Friendly Health System (AFHS) movement continues to grow in the United States as more health systems implement the 4Ms framework. Despite this growth, there are relatively few studies that evaluate outcomes related to AFHS implementation. This study assessed patient satisfaction with AFHS by analyzing the rate at which patients returned to the clinic for future health care, serving as a measure of quality.

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Objective: To evaluate the association between the expanded lymphoid profile and inborn errors of immunity using flow cytometry.

Methods: Observational and cross-sectional, case-control study, carried out in patients with a diagnosis or clinical suspicion of inborn errors of immunity, treated at the Santísima Trinidad Children's Hospital in Córdoba, Argentina, from August 2021 to November 2022. Clinical data were collected, and peripheral blood samples were obtained for flow cytometry analysis, using the PIDOT tube, to identify lymphocyte subpopulations.

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Social insects offer powerful models to investigate the mechanistic foundation of elaborate individual behaviors comprising a cooperative community. Workers of the leafcutter ant genus provide an extreme example of behavioral segregation among many phenotypically distinct worker types. We utilize the complex worker system of to test the molecular underpinnings of behavioral programming and, in particular, the extent of plasticity to reprogramming.

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Article Synopsis
  • - Biosimilars can greatly improve access to biologic treatments in Latin America, but their adoption is hindered by misunderstandings, regulatory issues, and insufficient monitoring of their use.
  • - A panel of experts recommended enhancing regulations, improving transparency, establishing solid monitoring systems, and fostering collaboration among various stakeholders to better educate about the benefits of biosimilars.
  • - To successfully integrate biosimilars and their interchangeability, Latin American countries need to close knowledge gaps and biases among healthcare providers and patients, which can be achieved through effective communication and real-world evidence.
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Covalent labeling methods coupled to mass spectrometry have emerged in recent years for studying the higher order structure of proteins. Quantifying the extent of modification of proteins in multiple states (i.e.

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