Variable number tandem repeat (VNTR) polymorphisms of the human neonatal IgG Fc receptor α-chain gene (FCGRT) are known to influence the expression levels of FCGRT and IgG in serum. Monkeys are considered to be a relevant biological model for studying the effects of immunobiological drugs. The study determined the functional VNTR polymorphisms of the FCGRT gene in 109 male rhesus macaques from the nursery of the Kurchatov Complex of Medical Primatology.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
February 2024
Objective: To analyze spontaneous behavior in 36 male rhesus macaques during formation of alcoholic motivation under free choice.
Material And Methods: The model composed the initiation stage with the provision of an aqueous ethanol solution of increasing concentration from 1 to 4% with a sweetener and restricted access to the tap water supply and the subsequent stage of the formation of alcoholic motivation with a free choice between 4% ethanol solution without sweetener and water. The behavior was recorded by the «One-Zero» method with ethogram compiled in accordance with the behavioral peculiarities of rhesus monkeys when housed individually.
Human rs6265 (196G>A) polymorphism in the BDNF gene is associated with many clinically significant phenotypic manifestations. Rhesus monkey (Macaca mulatta) has a functionally significant rs309950446 ( 136G>A) polymorphism. To determine this polymorphism in macaques, we used mismatch amplification mutation assay (MAMA)-PCR method with non-complementary nucleotide to the template chain at the 3rd position from the 3'-end of the allele-specific primers (mismatch primers), which allowed the best discrimination of the alleles.
View Article and Find Full Text PDFFour new species of Laonice (Annelida: Spionidae) are described from the southern and southeastern coasts of Asia: L. (Laonice) persica sp. nov.
View Article and Find Full Text PDFThe continental shelf of the northeastern Barents Sea is presently experiencing a weak influx of Atlantic water from the west. In recent times, warming in Arctic regions has led to an increase in extended ice-free periods in this area, instead of significantly elevating water temperatures. The implications of this phenomenon on the structure and functioning of benthic communities were investigated during the autumn of 2019 within the Makarov Strait, located in the southwestern part of the St.
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