Publications by authors named "L A Papp"
Article Synopsis
- Radical prostatectomy (RP) is a standard treatment for localized prostate cancer, but accurately detecting extraprostatic extension (EPE) before surgery is difficult, which can lead to suboptimal treatments.
- This study explores using explainable machine learning to improve EPE detection by analyzing data from newly diagnosed prostate cancer patients who underwent PET/MRI imaging and subsequent surgery.
- The results showed machine learning models outperformed traditional imaging methods in predicting EPE, which could lead to better clinical decision-making and improved patient outcomes.
Article Synopsis
- This study looked at how to better grade prostate cancer using a new machine learning model that combines different types of medical data.
- They analyzed information from 146 patients who had specific imaging tests before surgery and created five different models to see which worked best.
- The best model, called the random forest model, outperformed the usual grading method, helping doctors find patients at higher risk for more personalized treatment.
Background: Limited prior research to examine co-occurrence of prescription drug misuse with other substances among young adults has documented outcomes that are more problematic for those with higher rates of co-ingesting alcohol. There is a need to understand how college students in this period of heightened risk use other salient substances in moments of their prescription misuse in daily life.
Method: Young-adult college students who engaged in recent prescription misuse ( = 297) completed ecological momentary assessment (EMA) over a 28-day period, resulting in 23,578 reports.
The role of model organisms such as yeasts in life science research is crucial. Although the baker's yeast () is the most popular model among yeasts, the contribution of the fission yeasts () to life science is also indisputable. Since both types of yeasts share several thousands of common orthologous genes with humans, they provide a simple research platform to investigate many fundamental molecular mechanisms and functions, thereby contributing to the understanding of the background of human diseases.
View Article and Find Full Text PDFIn this study, we examined over 200-year-old L. specimens under different environmental conditions. The overall aim was to explore which factors influence their vitality and general fitness in urban environments and thus their ability to tolerate stressful habitats.
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