Publications by authors named "L A Mongiat"
Polycyclic aromatic hydrocarbons (PAHs) are widespread globally, primarily due to long-term anthropogenic pollution sources. Since PAHs tend to accumulate in soil sediments, liverwort plants, such as , are susceptible to their adverse effects, making them good models for bioindicators. The aim of this study was to probe the impact of anthracene, a three-ring linear PAH, on the growth parameters of and the relationship established with the internalization of the pollutant throughout the phenology of the plant.
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- Adult neurogenesis in zebrafish may act as a mechanism facilitating continuous growth and adaptability in response to environmental changes.
- Training adult zebrafish in a cue-guided maze improved their performance and increased neuron production in specific brain regions, indicating a connection between learning and neurogenesis.
- The study suggests that learning boosts neurogenesis through enhanced cell proliferation and protection of new neurons, emphasizing the role of adult neurogenesis in brain plasticity.
Alterations in the social environment, such as isolating an individual that would normally live in a social group, can generate physiological responses that compromise an individual's capacity to learn. To investigate this, we tested whether social isolation impairs learning skills in the rainbow trout. We show that rainbow trout can achieve an active avoidance (AA) learning program with inter-individual variability.
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- Compartmental models help understand neuron computations but often require extensive tuning for versatility.
- The T2N interface allows for easier control of NEURON with Matlab, creating stable and robust models over different neuron types and conditions.
- The new model for dentate granule cells effectively simulates various experimental data and offers potential applications in large-scale network studies and degeneracy research.
Developing granule cells (GCs) of the adult dentate gyrus undergo a critical period of enhanced activity and synaptic plasticity before becoming mature. The impact of developing GCs on the activity of preexisting dentate circuits remains unknown. Here we combine optogenetics, acute slice electrophysiology, and in vivo chemogenetics to activate GCs at different stages of maturation to study the recruitment of local target networks.
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