[The effectiveness of short and prolonged course treatment of anxiety with Anvifen].

Objective: To determine the effectiveness of the treatment of anxiety disorder with Anvifen (aminophenylbutyric acid) in a short (21 days) and prolonged (60 days) course of treatment.

Material And Methods: Patients were randomly divided into two groups: a short course (21 days) of treatment with Anvifen (group 1) and a prolonged course (60 days) of treatment with Avifen (group 2). In each group, patients were divided into age subgroups: 20-40 years old (1a - =30, mean age 32 [21; 39], 2a - =30, mean age 33 [23; 38] years) and 41-70 years (1b - =30, mean age 62 [51; 67] years; 2b - =30, mean age 60 [51; 68] years).

[Effectiveness of the anxiolytic Anvifen in the treatment of post-COVID brain fog].

Objective: To determine the significance of anxiety disorder and comorbid disorders in patients with post-covid brain fog, to determine the effectiveness of the GABAergic nootropic drug with an anxiolytic effect - Anvifen.

Material And Methods: 92 post-COVID-19 patients with no organic brain damage who complain of brain fog 12 weeks after the onset of COVID-19 symptoms. Group 1 (=40; 43.

[Intrinsic UV-fluorescence of lysozyme and microenvironment of its tryptophan residues].

The localization of tryptophan residues in hen egg-white lysozyme macromolecule was studied on the basis of the known 3D structure. The polarity and packing density of their microenvironments were evaluated. All residues that can affect the tryptophan fluorescence were revealed.