Publications by authors named "L A M J G van Riel"

Background MRI-guided focal laser ablation (FLA) is a promising treatment in localized prostate cancer (PCa). MRI-guided micro-US FLA shows potential for outpatient use, but its clinical application remains unexplored. Purpose To evaluate the safety, feasibility, and 12-month functional and oncologic outcomes of MRI-guided micro-US transperineal FLA in localized PCa and to assess the accuracy of micro-US in showing lesions depicted at MRI with Prostate Imaging Reporting and Data System (PI-RADS) score of 3 or higher.

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Objective: To describe the shape and volume of ablations created by transperineal laser ablation (TPLA) using multiple fiber configurations. Furthermore, to measure the change in the ablation zone and prostate volume over time, and to assess inter-patient ablation volume variability.

Methods: Data from a prospective, single-center, interventional pilot study including 20 patients is used.

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Background: Focal laser ablation (FLA) serves as a targeted therapy for prostate cancer (PCa). Clinical studies have demonstrated significant variations in ablation volumes with consistent fiber configurations. Consequently, a prediction model is needed for the safe application of FLA in treating PCa.

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Article Synopsis
  • This study looks at problems with positioning needles during prostate cancer treatment, focusing on two main issues: obstacles from the pubic arch and mistakes in needle placement.
  • The researchers found 50 articles and discovered that the amount of interference from the pubic arch can vary based on a person's prostate size and position, while some treatments caused more needle misplacements than others.
  • Current guidelines on how to position needles are unclear and differ from one hospital to another, but using special steerable needles could help make the procedures safer and more accurate.
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