Publications by authors named "L A Litzky"

Article Synopsis
  • Poor agreement among lung transplant pathologists in assessing rejection has been noted, making inter-rater reliability crucial for effective patient care and clinical trial inclusion criteria.
  • A survey and diagnostic sessions with nine pathologists from eight centers evaluated their practices and scoring of high-risk histopathologic findings related to chronic lung allograft dysfunction (CLAD).
  • The results showed good inter-rater reliability for identifying high-risk findings after these alignment sessions, indicating that collaborative discussions improved consensus among pathologists.
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Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether differential gene expression of pulmonary artery ECs (PAECs) can discern disease subtypes, progression and pathogenesis. We aimed to further validate our previously described method to propagate ECs from right heart catheter (RHC) balloon tips and to perform additional PAEC phenotyping.

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Post-acute sequelae of COVID-19 (PASC, "Long COVID") pose a significant global health challenge. The pathophysiology is unknown, and no effective treatments have been found to date. Several hypotheses have been formulated to explain the etiology of PASC, including viral persistence, chronic inflammation, hypercoagulability, and autonomic dysfunction.

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