The value of MRI in differentiating ovarian clear cell carcinoma from other adnexal masses with O-RADS MRI scores of 4-5.

Objective: To assess the utility of clinical and MRI features in distinguishing ovarian clear cell carcinoma (CCC) from adnexal masses with ovarian-adnexal reporting and data system (O-RADS) MRI scores of 4-5.

Methods: This retrospective study included 850 patients with indeterminate adnexal masses on ultrasound. Two radiologists evaluated all preoperative MRIs using the O-RADS MRI risk stratification system.

Reduced SARS-CoV-2 Infection Rates in Lab Workers Conducting Nucleic Acid Testing: Controlling for the Healthy Worker Effect.

Background: During the COVID-19 outbreak in December 2022 in China, some laboratory workers in SARS-CoV-2 nucleic acid testing (NAT) laboratories remained uninfected.

Objectives: To evaluate if the incidence of SARS-CoV-2 infection was reduced in laboratory workers who performed SARS-CoV-2 NAT, and whether this reduction resulted from the healthy worker effect.

Methods: This retrospective cohort study included 423 laboratory workers from 14 SARS-CoV-2 NAT laboratories in Xiamen, China.

An Unusual Meroterpenoid and Two New Steroids from Fungus Penicillium fellutanum and Their Bioactivities.

An unusual clathrate-type meroterpenoid isoatlantinone A (1), two new steroids acrocalysterols E (2) and F (3), together with fifteen known compounds (4-18) were separated from a plant-associated fungus Penicillium fellutanum. Their structures and absolute configurations were established based on spectroscopic data (NMR and HRESIMS), electronic circular dichroism (ECD) and modified Mosher's method. Notably, compound 1 represents an unusual highly oxygenated meroterpenoid derivative with a unique caged bioxatetracyclo-[6.

Design and alignment of a space gravitational wave detection telescope based on aberration scale control.

Regulating the proportion of low-order aberrations within total aberrations can effectively alter the tilt-to-length (TTL) coupling noise in a space gravitational wave telescope. Nevertheless, the low-order aberration ratio is disrupted during the actual manufacturing of the telescope. To address this issue, we analyzed the impacts of wavefront errors and low-order aberration proportions on the TTL coupling noise, determined the design requirements, and designed a 400 mm-aperture space gravitational wave telescope optical system.

A bHLH transcription factor RrUNE12 regulates salt tolerance and promotes ascorbate synthesis.

RrUNE12 binds to the RrGGP2 promoter to facilitate biosynthesis of AsA in Rosa roxburghii fruit. Furthermore, RrUNE12 upregulates antioxidant-related genes and maintains ROS homeostasis, thereby improving tolerance to salt stress. L-ascorbic acid (AsA) plays an essential role in stress defense as a major antioxidant in plant cells.