Publications by authors named "L A Levine"
Background: Cesarean delivery remains the most common obstetrical procedure with more than 250,000 patients in the US undergoing cesarean following labor induction annually. Here, we evaluated the impact of prospectively implementing a standardized labor induction protocol on cesarean delivery rates.
Methods: This multi-site type I hybrid effectiveness-implementation study compared 2 years before (PRE) and 2 years after (POST) implementation of a standardized labor induction protocol at two hospitals within the University of Pennsylvania Health System (2018-2022).
Postpartum Readmissions Among Patients with Adult Congenital Heart Disease.
Am J Obstet Gynecol MFM
December 2024
Background: Given risks associated with CHD in the postpartum period, epidemiologic data identifying risk factors and timing of complications may be useful in improving postpartum care.
Objective: The objectives of this study were to determine timing of, risk factors for, and complications associated with 60-day postpartum readmissions following deliveries with maternal congenital heart disease (CHD).
Study Design: The 2010-2020 Nationwide Readmissions Database was used for this retrospective cohort study.
Article Synopsis
- A study examined how inflammatory diets impact cardiovascular health, particularly in relation to adverse pregnancy outcomes (APOs) like preterm birth and gestational diabetes.
- Data from over 3,200 pregnant individuals showed that higher inflammatory diet scores correlated with increased body mass index, waist circumference, blood pressure, triglycerides, and insulin levels, along with lower good cholesterol levels.
- The study found that the negative impact of inflammatory diets on cardiometabolic health was more pronounced in individuals who experienced APOs during pregnancy.
Objective: Many patients with melanoma treated with immune checkpoint inhibitors (ICIs) do not derive response. Preclinical and retrospective studies identified that inhibition of the cyclooxygenase (COX) pathway may improve response to ICI treatment.
Methods: This prospective single site phase II trial accrued patients with advanced/metastatic melanoma.
Study Objective: To evaluate patient-level differences and decision making surrounding subsequent pregnancies (SSP) after peripartum cardiomyopathy (PPCM).
Design: Mixed methods approach to evaluate quantitative demographic and clinical differences between patients with and without a SSP and to qualitatively describe the decision-making regarding a SSP with a survey component.
Setting/participants: 220 PPCM cases within the University of Pennsylvania Health System.