Diabetes is not a negative prognostic factor for 30-days mortality after surgery for acute type A aortic dissection.

Background: The correlation between diabetes and aortic dissection is not fully understood yet, although in literature many studies have suggested that there may be an association between the two conditions. The purpose of this study is to evaluate whether diabetes represents a short- and long-term risk factor for mortality from type A acute aortic dissection.

Materials And Methods: A total of 340 patients with the diagnosis of type A acute aortic dissection underwent aortic surgery between January 2002 and March 2023.

Analysis of current mortality risk scores for acute type A aortic dissection: The Siena experience.

Objective: In literature, various risk scores have been described to predict in-hospital mortality of patients undergoing surgery for acute type A dissection. We want to evaluate which factors are most correlated with a negative outcome and testing the validity of the current scores in literature analyzing our experience of over 20 years in the surgery of type A aortic dissections.

Materials And Methods: A total of 324 patients were included in the study.

Long-termculture of 3D brain tissue model based on chitosan thermogel.

Methods for studying brain function and disease heavily rely onanimal models,tissue slices, and 2D cell culture platforms. These methods all have limitations that significantly impact the clinical translatability of results. Consequently, models able to better recapitulate some aspects ofhuman brain are needed as additional preclinical tools.

Transapical total aortic arch replacement with three-branched endograft for penetrating aortic ulcer.

An 80-year-old man with a chronic penetrating atherosclerotic ulcer was not a candidate for open surgical repair owing to the presence of diffuse vascular atherosclerosis and a deep ulcerative lesion originating at the level of the aortic arch concavity. No appropriate endovascular landing zone was present in arch zones 1 or 2. However, a totally endovascular branched arch repair involving transapical delivery of the three branches was successful.