Electrocardiographic predictors of response to sacubitril/valsartan therapy in heart failure with reduced ejection fraction.

Background: Sacubitril/valsartan (SV) is currently recommended as a first-line therapy in patients with heart failure and reduced ejection fraction (HFrEF) due to its significant clinical and prognostic benefit; however, not all patients respond to therapy and predictors of clinical response to SV remain under-studied.

Aims: To identify electrocardiographic (ECG) predictors of response to SV therapy in HFrEF patients.

Methods: A retrospective analysis of a hospital heart failure registry was undertaken.

College Warrior Athlete Initiative and academic nursing.

The College Warrior Athlete Initiative (CWAI) determined if a key element of military occupational culture, referred to as the "battle-buddy" concept of pairing college athletes with veterans, could be applied to Student Service Members/Veterans (SSM/V) health promotion. Fifty veterans of fifty-seven enrolled completed the program in seven separate cohorts between 2016 and 2017. The veteran-student athlete pairs or small groups exercised twice a week for 75 min under the supervision of a certified athletic trainer and attended wellness classes.

Evaluating competence and confidence using simulation technology.

This article discusses the role of simulation training in educating nurses and reducing clinical errors and describes a research project designed to determine the effectiveness of deliberate practice and simulation technology.

Near-infrared monitoring of roller compacted ribbon density: Investigating sources of variation contributing to noisy spectral data.

The aim of this study was to highlight how variability in roller compacted ribbon quality can impact on NIR spectral measurement and to propose a simple method of data selection to remove erroneous spectra. The use of NIR spectroscopy for monitoring ribbon envelope density has been previously demonstrated, however to date there has been limited discussion as to how spectral data sets can contain erroneous outliers due to poor sample presentation to the NIR probes. In this study compacted ribbon of variable quality was produced from three separate blends of microcrystalline cellulose (MCC)/lactose/magnesium stearate at 8 Roll Force settings (2-16kN/cm).