Publications by authors named "L A Khvan"

The article presents a description of a patient with chronic HCV infection and multiple extrahepatic manifestations, which manifested in dynamics and were recorded with a different sequence during 15 years of follow-up. In the patient we observed, the most frequently recorded extrahepatic manifestations were verified: porphyria cutanea tarda, mixed cryoglobulenemia, and utoimmune thyroiditis. Chronic HCV infection is often diagnosed in the presence of psoriasis was assessed as a paraneoplastic disease.

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We studied safety and clinical efficacy of transplantation of autologous bone marrow cell in complex therapy of 158 patients with chronic hepatitis and cirrhosis of the liver. The efficiency of cell therapy was assessed in 12 months after single injection of the cells. The positive response (alleviation of liver cirrhosis or stabilization of the pathological process) was observed in 70% cases.

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Article Synopsis
  • The study examines porphyrin metabolic disturbances in liver cirrhosis patients with different causes, aiming to assess their diagnostic and prognostic significance.
  • Out of 71 patients, 62 exhibited porphyrin abnormalities, with higher rates observed in those with viral (86.7%) and alcoholic cirrhosis (94.1%).
  • The findings suggest that porphyrin metabolism can serve as a sensitive indicator for liver cirrhosis severity and could help in assessing prognosis, especially in advanced cases of the disease.
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