Locked-in syndrome is a rare neurological disorder. It is characterized by tetraparesis, paralysis of facial and masticatory muscles, anarthria and pseudobulbar syndrome with possible preservation of vertical movements of the eyeballs and blinking, as well as preservation of consciousness. A serious problem with the «locked-in person» syndrome is the inability of the patient to socialize, which causes him to experience no less suffering than from physical limitations.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
January 2025
Hemorrhagic transformation (HT) is a serious complication that worsens outcomes and increases mortality in patients with ischemic stroke (IS). HT can occur both spontaneously and after reperfusion therapy. Severe ischemic injury in IS is not sufficient in itself to cause HT; one of the key elements in its development is reperfusion.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
August 2024
The issues of effective treatment of ischemic stroke (IS) are relevant, since it leads to a high percentage of disability and mortality throughout the world. The article presents 4 cases of patients with various pathogenetic variants of IS that developed against the background of a new coronavirus infection COVID-19 (degree of lung damage: CT-0 and CT1). Due to the presence of symptomatic occlusion of a large artery, these patients successfully underwent cerebral angiography followed by mechanical thrombus extraction (MTE), after which a significant improvement in neurological symptoms was observed.
View Article and Find Full Text PDFAnnu Rev Anal Chem (Palo Alto Calif)
June 2023
Electrochemical additive manufacturing is an advanced microfabrication technology capable of producing features of almost unlimited geometrical complexity. A unique combination of the capacity to process conductive materials, design freedom, and micro- to nanoscale resolution offered by these electrochemical techniques promises tremendous opportunities for a multitude of future applications spanning microelectronics, sensing, robotics, and energy storage. This review aims to equip readers with the basic principles of electrochemical 3D printing at the small length scale.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
January 2023
Objective: To study of modern literature on the clinical and pathophysiological features of stroke in patients with a new coronavirus infection (COVID-19).
Material And Methods: Published data were searched in the electronic databases Medline (PubMed) and eLIBRARY for the period 2019-2022.
Results: It has been shown that patients with COVID-19 have a large number of risk factors for stroke, which may indicate that COVID-19 is a trigger for the development of the disease.