Gait asymmetry assessment through Eigen-Gait components on dissimilarity maps.

Motor impairments caused by neurological diseases have an important impact on gait, particularly on the coordination between left and right lower limbs. Deviation from normal gait is often measured to assess this impact on gross motor functions, and to monitor the progress of patients during rehabilitation. The concept of gait dissimilarity map is introduced to represent bilateral raw gait signals, while accounting for their respective spatiotemporal dynamics.

A novel gait quality measure for characterizing pathological gait based on Hidden Markov Models.

This study addresses the characterization of normal gait and pathological deviations caused by neurological diseases. We focus on the angular knee kinematics in the sagittal plane and we propose to exploit Hidden Markov Models to build a statistical model of normal gait. Such model provides a log-likelihood score that quantifies gait quality.

Clinical Gait Analysis: Characterizing Normal Gait and Pathological Deviations Due to Neurological Diseases.

This study addresses the characterization of normal gait and pathological deviations induced by neurological diseases, considering knee angular kinematics in the sagittal plane. We propose an unsupervised approach based on Dynamic Time Warping (DTW) to identify different normal gait profiles (NGPs) corresponding to real cycles representing the overall behavior of healthy subjects, instead of considering an average reference, as done in the literature. The obtained NGPs are then used to measure the deviations of pathological gait cycles from normal gait with DTW.

A physiological study to determine the mechanism of carbon dioxide clearance during apnoea when using transnasal humidified rapid insufflation ventilatory exchange (THRIVE).

Clinical observations suggest that compared with standard apnoeic oxygenation, transnasal humidified rapid-insufflation ventilatory exchange using high-flow nasal oxygenation reduces the rate of carbon dioxide accumulation in patients who are anaesthetised and apnoeic. This suggests that active gas exchange takes place, but the mechanisms by which it may occur have not been described. We used three laboratory airway models to investigate mechanisms of carbon dioxide clearance in apnoeic patients.