Publications by authors named "L A Harvey"
Background: Exposure to maternal stress and depression during pregnancy can have a marked impact on birth outcomes and child development, escalating the likelihood of preterm birth, lower birth weight, and various domains of physical and neurodevelopment.
Methods: The joint ECHO.CA.
The nutritional environment during fetal and early postnatal life has a long-term impact on growth, development, and metabolic health of the offspring, a process termed "nutritional programming." Rodent models studying programming effects of nutritional interventions use either purified or grain-based rodent diets as background diets. However, the impact of these diets on phenotypic outcomes in these models has not been comprehensively investigated.
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- Delirium is a common complication for older adults after hip fracture surgery, with a study analyzing patient data from 2015-2020 revealing inconsistent links between the type of anaesthesia used and the occurrence of delirium.
- Among the 35,252 patients studied, those who received general anaesthesia (40.6%) showed higher rates of delirium compared to those who received spinal or regional anaesthesia (35.7%).
- Adjustments for known confounders indicated a weak association between general anaesthesia and delirium, but an analysis addressing unmeasured factors found no significant causal link, suggesting more research is needed in this area.
Article Synopsis
- The study investigates the incidence and outcomes of hypothermic cardiac arrest (HCA) in an urban setting, contrasting with previous focus on wilderness cases.
- Among 171 eligible patients, 25% suffered HCA, with risk increasing significantly as core temperature decreased; HCA was seen in 6% of moderately hypothermic, 38% of severely hypothermic, and 89% of profoundly hypothermic patients.
- Witnessed HCA cases, particularly in prehospital or emergency department settings, showed favorable survival outcomes, with a 53% overall survival rate, and even higher (90%) for patients whose HCA occurred post-arrival in the ED.