Publications by authors named "L A Fern"
There has been little change to the standard treatment for osteosarcoma (OS) over the last 25 years and there is an unmet need to identify new biomarkers and novel therapeutic approaches if outcomes are to improve. Furthermore, there is limited evidence on the impact of OS treatment on patient-reported outcomes (PROs). ICONIC (Improving Outcomes through Collaboration in Osteosarcoma; NCT04132895) is a prospective observational cohort study recruiting newly diagnosed OS patients across the United Kingdom (UK) with matched longitudinal collection of clinical, biological, and PRO data.
View Article and Find Full Text PDFThe Sarcoma Assessment Measure (SAM) was developed as a sarcoma-specific patient-reported outcome measure to be used in clinical practice. We have reported in detail how SAM has been developed in collaboration with patients and healthcare professionals. The aim of this paper is to report the preliminary validation of SAM.
View Article and Find Full Text PDFIn England, health care policy promotes specialized age-appropriate cancer services for teenagers and young adults (TYA), for those aged 13-24 years at diagnosis. Specialist Principal Treatment Centers (PTCs) provide enhanced age-specific care for TYA, although many still receive all or some of their care in adult or children's cancer services. Our aim was to determine the patient-reported outcomes associated with TYA-PTC based care.
View Article and Find Full Text PDFArticle Synopsis
- The COVID-19 pandemic forced nurses to transition into new and often unfamiliar roles in intensive care due to a surge in critically ill patients, creating significant challenges.
- A survey conducted on redeployed nurses assessed their feelings about the change, revealing that while many felt a sense of duty and preparedness, a substantial number experienced anxiety about their new responsibilities and felt undervalued.
- The study highlighted that lack of training and feeling undervalued were key factors contributing to emotional exhaustion, emphasizing the need for proper support and training for nurses to prevent burnout.
Background: Time to diagnosis (TTD) of childhood soft tissue sarcoma (STS) is significantly associated with survival. This review aims to identify pre-diagnostic symptoms/signs to inform earlier diagnosis interventions.
Methods: Medline, Embase, Cochrane and Web-of-Science were searched between January 2010 and February 2021 for studies including children (<18 years) diagnosed with STS, with no language restrictions.