Effects of Trypanosoma brucei brucei infection and diminazene aceturate administration on the blood pressure, heart rate, and temperature of Wistar albino rats.

Background: This study was carried out to determine the blood pressure changes in experimentally Trypanosoma brucei brucei-infected Wistar albino rats and diminazene aceturate-treated rats.

Methods: Twenty-four rats were purchased and divided into four groups consisting of six rats each. Control group (CON) received 0.

Modulatory effects of melatonin and vitamin C on oxidative stress-mediated haemolytic anaemia and associated cardiovascular dysfunctions in rats.

Background Phenylhydrazine (PHE) in experimental animal models has been widely reported to cause haemolytic anaemia, via the induction of oxidative stress and thus causing deleterious cardiovascular complications. Hence, this study was designed to evaluate the possible modulatory role of melatonin (MLT) or vitamin C when co-administered with PHE. Methods Anaemia was established with PHE administration.

How do patients determine that their metered-dose inhaler is empty?

Study Objective: To evaluate how patients determined that pressurized metered-dose inhaler (pMDI) canisters were empty and to measure pMDI depletion under different circumstances in the laboratory.

Setting: Most of the study was performed in a university research laboratory.

Participants: Fifty consecutive patients attending the Brenner Children's Hospital Asthma Center were initially questioned regarding pMDI use, and they demonstrated their use of the inhaler.

Weights and blood profiles of the west African hinge-backed tortoise, Kinixys erosa and the desert tortoise, Gopherus agassizii.

The body weight and blood profile were determined in the adult wild West African hinge-backed tortoise, Kinixys erosa and the adult wild desert tortoise, Gopherus agassizii kept under identical environmental conditions. A comparison between sexes showed the male K. erosa had significantly higher packed cell volume and haemoglobin concentration and lower body weight and plasma alkaline phosphatase values than the female, while no significant sex differences appeared in these parameters in G.

Stimulation of the production of progesterone by the corpus luteum of the ewe by the perfusion of melatonin in vivo and by treatment of granulosa cells with melatonin in vitro.

The ability of melatonin to stimulate luteal steroidogenesis directly in the ewe was investigated by using a perfusion cannula system in vivo and luteinised granulosa cells in vitro. Exposure to human chorionic gonodotrophin (hCG) or ovine luteinising hormone (oLH), as positive controls, significantly stimulated progesterone secretion by the perfused corpus luteum within 20 minutes and by granulosa cells after two days of culture. Melatonin perfused through the corpus luteum at a physiological concentration, significantly stimulated progesterone secretion but the response was not as rapid as that to hCG.