Publications by authors named "L A Dueva"

The authors proved "Rokadovskaya" water to be efficient in complex therapy of workers with occupational and industrially mediated diseases. The effects included normalization and activation of antioxidant and phagocytic functions of peripheral neutrophils. Immunologic effects on immune cells and humoral immunity parameters were studied for various nosologic entities.

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Studies on pathogenetic mechanisms of development, formation and course of occupational diseases revealed pathomorphosis of major specification forms (diseases of bronchopulmonary system, skin, nervous system, locomotory apparatus). Developing pathomorphosis of occupational and occupationally mediated diseases is caused by changed work conditions, lower acting concentrations and levels of occupational factors, influence of harmful ecologic factors, metabolic features, immune state, individual sensitivity to occupational and environmental factors.

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Complex clinical examination of aluminium production workers having broncho-pulmonary diseases revealed immunologic criteria of toxic dust bronchitis, diffuse pneumosclerosis and secondary infection-dependent bronchial asthma, caused by combination of occupational hazards. Contribution of allergic environmental factors was shown as they deplete immune reserves in the workers. The authors proved efficiency of contemporary immune modulator polyoxydonium, when included into the complex therapy.

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Galvanic production workers appeared to have mainly humoral immunity activated--sensitization to nickel, reliable prevalence of immune disorders in males over females, significant influence of immune overstrain on frequency of acute respiratory infections and allergic conditions. The authors justified approaches to safe immune prophylaxis of diseases in workers.

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Complex clinical examination of patients with occupational hypersensitivity pneumonitis caused by inorganic, organic and mixed dust helped to spicify variants of the disease--with prevailing bronchial asthma, chronic obstructive bronchitis, recurrent pneumonia, chronic respiratory failure.

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