Publications by authors named "L A Copeland"
Combined immune checkpoint blockade (ICB) and chemoradiation (CRT) is approved in patients with locally advanced cervical cancer (LACC) but optimal sequencing of CRT and ICB is unknown. NRG-GY017 (NCT03738228) was a randomized phase I trial of atezolizumab (anti-PD-L1) neoadjuvant and concurrent with CRT (Arm A) vs. concurrent with CRT (Arm B) in patients with high-risk node-positive LACC.
View Article and Find Full Text PDFResistant starch (RS) has been shown to modulate intestinal microbiota in animal models in ways that could reduce the effects of dysbiosis-related diseases. However, the mechanism of how this is achieved is not understood. The present study aimed to reveal the mechanism of how RS mitigates dextran sulfate sodium (DSS)-induced colitis in mice by using a starch-lipid complex (RS type 5), with an RS type 2 from high-amylose maize starch as a comparison.
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- Patient portals, like MyChart, are becoming popular in the U.S. healthcare system, but it's unclear how patients feel about using them for research and health-related tasks.
- A survey of 105 patients revealed that nearly all had used MyChart, primarily for checking lab results and messaging their healthcare providers, with less interest in medication details or health education.
- Most participants expressed willingness to engage in research activities through MyChart, such as answering surveys and health assessments, with significant interest in discussing topics like sleep and stress via the portal.
Burnout is a well-recognized problem among resident physicians. The COVID-19 pandemic impacted the dynamics of the patient/resident relationship and introduced new stressors for medical trainees, such as new restrictions in the hospital, increased patient death, and uncertainty around safety. There is limited research on the implementation of group therapy for residents to address issues of wellbeing and burnout during the pandemic.
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- Before the COVID-19 pandemic, the U.S. Department of Veterans Affairs (VA) had the largest telehealth program in the U.S., and the pandemic prompted an expansion of telehealth to help veterans, particularly those experiencing housing instability (HI), access diabetes care.
- The study used mixed methods, including data analysis and interviews, to assess how diabetes care delivery via VA Video Connect (VVC) changed and which sociodemographic factors influenced usage among veterans with HI from 2019 to 2022.
- Findings revealed that younger, non-rural, and certain demographic groups of veterans were more likely to utilize VVC, while barriers to its use included in-person care limitations and the need for enhanced education and technology