Diagnosing dementia: perspectives of primary care physicians.

As few as 50% of dementia cases are diagnosed by physicians. This study investigated how primary care physicians assess patients for dementia and identified barriers to dementia diagnosis in the primary care setting. Seventy-eight physicians in three geographic areas participated in 18 focus groups.

Painless hematuria and urethral discharge secondary to ectopic prostate.

We report a case of ectopic prostatic tissue found in the penile urethra of a 16-year-old boy. A literature review and discussion of this rare entity are presented.

Oral immunization with sperm antigens: possible therapy for sperm antibodies?

Young adult male CD-1 mice were given intraperitoneal injections (IP) of saline (controls) and pooled sperm or seminal plasma of two autoimmune infertile men and two nonautoimmune fertile men (n = 40 per treatment). Other mice received only an oral challenge with the same antigens (oral controls; n = 20 per treatment). Three weeks after the booster challenge (day 36), 20 mice in each group were orally immunized with the antigens, whereas the other 20 were not (IP controls).

Limb defects in gray short-tailed opossums (Monodelphis domestica) following postnatal injection with ethanol or saline.

Because the hindlimbs of marsupials at birth are in an embryonic stage of development, this group can prove useful for studies of limb teratology. In this study, injection of neonatal gray opossums with 2 mg ethanol (ETOH) or saline (SAL) in the right or left hindquarter resulted in defects of the associated limb in 44% of ETOH animals and 16% of SAL animals. Affected SAL animals showed gait abnormalities, foot clubbing, and moderately reduced limb size.

Growth characteristics of human Wilms' tumor in nude mice.

Ten Wilms' tumors (WT) were heterotransplated into athymic (nude) mice. Eight of the tumors (80%) grew and were serially passaged as many as 20 times. The histology of the primary heterotransplants resembled that of the surgically excised tumors (seven classical and one anaplastic).