Publications by authors named "L A Christman"
This study aimed to determine whether a polyphenol-rich cranberry beverage affects skin properties, lipids, and the microbiome in women using a randomized, double-blinded, placebo-controlled, cross-over design. Twenty-two women with Fitzpatrick skin types 2-3 were randomized to drink a cranberry beverage or placebo for six weeks. After a 21-day washout, they consumed the opposite beverage for six weeks.
View Article and Find Full Text PDFRetraction of 'Dealcoholized muscadine wine was partially effective in preventing and treating dextran sulfate sodium-induced colitis and restoring gut dysbiosis in mice' by Hao Li , , 2023, , 5994-6011, https://doi.org/10.1039/D3FO00047H.
View Article and Find Full Text PDFEmerging data suggest that post-traumatic stress disorder (PTSD) arises from disrupted brain default mode network (DMN) activity manifested by dysregulated encephalogram (EEG) alpha oscillations. Hence, we pursued the treatment of combat veterans with PTSD (n = 185) using an expanded form of repetitive transcranial magnetic stimulation (rTMS) termed personalized-rTMS (PrTMS). In this treatment methodology spectral EEG based guidance is used to iteratively optimize symptom resolution via (1) stimulation of multiple motor sensory and frontal cortical sites at reduced power, and (2) adjustments of cortical treatment loci and stimulus frequency during treatment progression based on a proprietary frequency algorithm (PeakLogic, Inc.
View Article and Find Full Text PDFArticle Synopsis
- Muscadine wine contains beneficial compounds like anthocyanins and flavonols and this study investigates its effects on colitis in mice and the gut microbiome.
- Male C57BL/6 mice were fed a specific diet with dealcoholized muscadine wine during different phases (prevention, treatment, combined) while colitis was induced with DSS.
- Results showed that dealcoholized muscadine wine reduced inflammation, improved gut health, and enhanced the gut microbiome, particularly in the group that had both prevention and treatment.
Article Synopsis
- This study explored how muscadine grape polyphenols (MGP) and muscadine wine polyphenols (MWP) affect arthritis in mice, showing they can delay its onset and lessen severity.
- MGP and MWP decreased levels of inflammatory markers and improved joint health, reducing bone and cartilage damage in collagen-induced arthritis (CIA) mice.
- MWP was particularly effective in restoring gut microbiome balance, which is linked to inflammation and arthritis progression, suggesting dietary polyphenols could help manage arthritis in humans.