[Use of germ-free mice in experimental transplantation].

A comparative study of skin allografts was performed in germ-free A/Ola mice kept in boxes and in A/Ola and BALB mice raised in ordinary conditions. Skin graft (of C57B1/6 mice) in A/Ola and BALB mice raised in ordinary conditions was shown to reject 16-21 and 12-18 days after the transplantation, respectively without cyclophosphamide (CP) use. CP application in BALB mice, grown in ordinary conditions, prolonged the lifespan of grafts to 12-29 days.

[Effect of different diets on blood protein indices in gnotobionts].

The protein content in the diet affects the amount of serum protein and fraction distribution in gnotobiots. Germ-free pigs and guinea-pigs which received the diet containing the least amount of protein showed an abrupt decrease in the total protein level in blood serum. As regards the content of alpha- and beta-globulins, no significant differences were found in blood serum of experimental animals.