Publications by authors named "L A Blunt"
Article Synopsis
- This study investigates how different ratios of excipients like lactose, microcrystalline cellulose, and dicalcium phosphate affect the swelling and drug release of propranolol hydrochloride (PPN) from polyethylene oxide (PEO) matrix compacts.
- The researchers used microscopy to analyze the compact surfaces and conducted dissolution studies to assess how the excipient ratios influenced hydration rates and drug release dynamics.
- Findings indicate that modifying the amount of PEO and the type or ratio of excipients can significantly affect drug release rates, highlighting the innovative use of UV dissolution imaging for optimizing formulations.
Many methods of ballistic toolmark comparison rely upon comparison using 2D greyscale imaging. However, newly emerging analysis methods such as areal surface analysis now utilise an extra dimension of measurement allowing the surface heights/depths of unique toolmark features to be recorded in a densely populated (x,y,z) array for a 3D/areal quantitative comparative analysis. Due to this step change, the colloquialism in referring to the crater produced at the centre of the primer during firing as a "firing pin impression" has become a misnomer, leading some to believe that this toolmark is produced via a single process, where the critical variable is the condition of the firing pin.
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- The study aimed to evaluate how different printing orientations affect the fit and gaps of a 3-unit interim fixed partial denture created using two additive manufacturing methods compared to traditional milling.
- A digital design was printed using stereolithography (SLA) and digital light processing (DLP) technologies, with measurements taken for gaps in various orientations, while milling served as a control.
- Results indicated that SLA produced comparable fit to milling across all orientations, whereas DLP showed significantly larger gaps, suggesting SLA is more reliable for dental applications.
Statement Of Problem: Strength-gradient zirconia combining 3 zirconia formulations with different flexural strengths has been reported to have outstanding mechanical properties. However, data concerning the effect of different sintering protocols on the fracture strength of 3-unit monolithic gradient zirconia fixed partial dentures (FPDs) are sparse.
Purpose: The purpose of this in vitro study was to test the effect of different sintering protocols on the fracture strength of 3-unit monolithic gradient zirconia FPDs.
Statement Of Problem: Polyetheretherketone (PEEK) has been increasingly used as a framework material in prosthetic dentistry. However, data on the marginal and internal fit of PEEK restorations fabricated by using either the computer-aided design and computer-aided manufacturing (CAD-CAM) or heat-pressing technique are sparse.
Purpose: The aim of this in vitro study was to assess the marginal and internal fit of milled and pressed PEEK single crowns by using microcomputed tomography (μCT).